About this deal
The US Department of Veterans Affairs recognized for the first time that a veteran acquired Hepatitis C from his military jet injections and awarded service-connection for his disability. This invention relates to needleless syringes for use in delivering particles into target tissue of a subject, for example skin or mucosa. In addition, it may be desirable to include a charged lipid and/or detergent in the pharmaceutical compositions.
mm for the first and second convergences respectively, equating to flow cross-sectional area ratios of 1:6.You’ll find these terms used to describe products like pens and other devices sold online to inject fillers at home. the chamber of increased cross-section is thought to provide a discontinuity to the gas flow which leads to the creation within the chamber of a transsonic jet, which jet passes through the chamber and attaches to the walls of the nozzle bore 3 in the region of the second convergence 9 .
Although not shown, the sonic nozzle 4 may be held in place within the central aperture of the main body 1 by cooperating screwthreads, or an interference fit in combination with a downstream shoulder formed by the main body 1. the particles are more uniformly dispersed over the target and the maximum penetration is still 250 ⁇ m. a gas/particle exit nozzle bounding said gas flow path for the acceleration therealong of the drawn in particles entrained in the gas. the convergence 5 ′ causes a reduction in gas pressure, in use, due to the Venturi effect such that there is, in use, a pressure differential across the powder cavity 55 . The upstream end of the nozzle 2 forms a second convergence or constriction 9 to the flow of gas through the main body 1.A method of distributing particles in a flow of gas and a needleless syringe for use in the needleless injection of particles into the skin or mucosa of a vertebrate subject are disclosed.